Top 7 Advantages of Pullulan Capsules Over Gelatin Alternatives

Mimei Biotechnology
Jul/11/2025
Top 7 Advantages of Pullulan Capsules Over Gelatin Alternatives
Pullulan capsules outperform gelatin in oxygen resistance, plant-based formulation, bioavailability, and more. This article explores the top 7 benefits, reinforced by scientific data and highlights from Shandong Mimei Biotechnology Co., Ltd., a leading innovator in sustainable capsule production and biopolymer technology.

In the increasingly health-conscious and environmentally aware global supplement market, the choice of capsule material has transcended mere packaging. It now symbolizes brand identity, quality assurance, and consumer trust. Among the frontrunners challenging the traditional gelatin monopoly is pullulan — a natural, plant-based polysaccharide with exceptional functional properties. Let’s unpack the top 7 advantages of pullulan capsules over gelatin alternatives, reinforced by research data and a glance into the innovation driven by Shandong Mimei Biotechnology Co., Ltd.


1. Superior Oxygen Barrier: Extended Shelf Life and Product Stability

One of the most striking advantages of pullulan capsules is their excellent oxygen barrier property. Pullulan has been proven to offer 6-8 times more oxygen impermeability compared to gelatin, effectively shielding sensitive ingredients like probiotics, enzymes, and fish oil from oxidation.

Capsule TypeOxygen Permeability (cc/m²/day/atm)
Gelatin~120
Pullulan~15

This superior barrier extends shelf life and preserves bioactive efficacy without resorting to synthetic preservatives. For nutraceutical companies and consumers alike, that means more reliable potency over time.


2. 100% Plant-Based and Vegan Friendly

As more consumers lean into ethical and plant-based lifestyles, pullulan answers the call with sincerity. Derived from tapioca via fermentation using Aureobasidium pullulans, pullulan capsules are entirely free from animal-derived ingredients. In contrast, gelatin is extracted from bovine or porcine skin and bones, making it unsuitable for vegans, vegetarians, or certain religious groups.

AttributeGelatin CapsulesPullulan Capsules
Animal-FreeNoYes
VeganNoYes
Kosher/Halal CertifiedOften NoYes

Pullulan capsules' compatibility with kosher, halal, and organic certifications has made them a popular option in markets with strict dietary restrictions, offering both inclusivity and purity.


3. Tasteless, Odorless, and Inert: Ideal for Sensitive Formulations

Another benefit that's often overlooked but significantly valued in practice is that pullulan is tasteless, odorless, and chemically inert. It doesn’t interfere with the content inside, making it ideal for sensitive, strongly flavored, or volatile compounds.

Gelatin, on the other hand, may introduce a slight taste or smell, especially under varying humidity or storage conditions. This seemingly minor sensory difference can greatly affect customer satisfaction and brand perception, especially in premium supplements.


4. Faster Dissolution Rate and Higher Bioavailability

Pullulan capsules boast a faster disintegration time in the digestive system, which translates into quicker bioavailability for active ingredients. According to clinical dissolution studies:

Capsule TypeAverage Disintegration Time (minutes)
Gelatin10-15
Pullulan5-9

Faster dissolution enables better absorption, particularly beneficial for time-sensitive compounds like herbal extracts, probiotics, and enzymes. This technical detail significantly elevates the therapeutic impact and is often a selling point for performance-focused nutraceuticals.


5. Outstanding Transparency and Aesthetic Appeal

When aesthetics meet functionality, pullulan shines—literally. The natural transparency and smoothness of pullulan capsules are unmatched, allowing brands to showcase colorful or visually appealing powder and beadlet formulations without compromising protection.

Moreover, pullulan’s clarity doesn’t come at the cost of stability, unlike HPMC (hydroxypropyl methylcellulose) capsules which may fog over time. This visual advantage plays well in high-end health and beauty markets, where appearance enhances perceived value.


6. Low Moisture Content: Stability in High-Humidity Climates

Pullulan capsules maintain structural integrity in varying humidity conditions due to their lower moisture content (~4-6%) compared to gelatin (~13-15%).

Capsule TypeTypical Moisture Content (%)
Gelatin13-15
Pullulan4-6

This characteristic makes pullulan the preferred choice for hygroscopic (moisture-sensitive) formulations such as herbal powders, effervescent mixes, or moisture-activated probiotics, especially in tropical regions or during international shipping.


7. Sustainability and Green Manufacturing

Pullulan production aligns with growing demands for sustainable manufacturing. It is derived from renewable plant sources using fermentation, a process inherently less intensive in terms of environmental footprint compared to animal-based gelatin extraction.

Shandong Mimei Biotechnology Co., Ltd. leads the charge in sustainable pullulan production. With 14 hectares of modern production space, 5 automated production lines, and an annual capacity of 3,000 tons of pullulan and 10 billion capsules, Mimei is not only one of the largest producers in China but also a pioneer in responsible biotechnology.

Mimei's facilities comply with GMP specifications and ISO22000, ISO14001, and ISO45001 standards. Furthermore, the company proudly holds organic, halal, and kosher certifications, catering to a wide international clientele.


A Glance into Shandong Mimei Biotechnology Co., Ltd.

Shandong Mimei Biotechnology Co., Ltd. isn’t just manufacturing capsules; it’s redefining what encapsulation means in a conscious age. With a professional R&D team of over 20 scientists and technologists, Mimei actively drives innovations in bio-polysaccharide applications. The company also produces 10,800 tons of dextran and 80 million pullulan bio-membranes annually, extending its influence beyond pharmaceuticals into bioplastics and food preservation.

Furthermore, Mimei is committed to social and environmental responsibility. The company actively contributes to public welfare and integrates energy-saving, emission-reduction principles into its operational ethos.


Conclusion: More Than Just a Capsule

The comparison between pullulan and gelatin capsules reveals more than just structural or functional differences—it highlights a paradigm shift in how the supplement industry approaches consumer health, ethical sourcing, and environmental stewardship. Pullulan capsules deliver on all fronts: performance, compatibility, sustainability, and global acceptability.

And with innovation-focused producers like Shandong Mimei Biotechnology Co., Ltd. leading the way, pullulan isn’t just a viable alternative—it’s a smarter, future-ready choice.

Looking to Elevate Your Product Line?Connect with Shandong Mimei Biotechnology Co., Ltd. today to explore high-quality OEM services and sustainable solutions in pullulan capsules.