Pullulan for Oral Care

Pullulan for Oral Care
Pullulan for Oral Care
Molecular formula
Plastic bags and carton vacuum packaging
Sealed and protected from light
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Pullulan, a polysaccharide, demonstrates remarkable attributes beneficial for dental product manufacturing. Its ability to form sturdy and transparent biofilms renders it ideal for crafting coatings that shield teeth against decay and erosion

Pullulan for Oral Care: A Versatile Solution for Dental Health

Oral hygiene plays a crucial role in overall health and well-being, with preventive measures such as regular brushing, flossing, and dental check-ups being paramount. However, advancements in oral care have led to the exploration of novel ingredients to enhance traditional oral hygiene practices. Pullulan, a naturally occurring polysaccharide produced by fungi, has emerged as a promising component in oral care products due to its unique properties and benefits.

Properties of Pullulan

Pullulan is a neutral, water-soluble polysaccharide composed of maltotriose units linked by α-(1→6) glycosidic bonds. This structure imparts several advantageous properties to pullulan, including excellent film-forming ability, moisture retention, and adhesion to various surfaces. Additionally, pullulan is biocompatible, non-toxic, and biodegradable, making it a safe choice for oral applications.

Pullulan used in Dental Products

Pullulan serves as an exceptional binding agent in diverse formulations like dental tablets and toothpaste, ensuring consistent texture and efficacy by facilitating even distribution of ingredients.

Moreover, leveraging its non-toxic and edible nature, pullulan finds application in producing dissolvable oral strips or films. These can be imbued with active compounds for breath freshening or targeted therapeutic delivery within the oral cavity. Furthermore, pullulan-based matrices enable tailored control over the release of active ingredients in dental products, facilitating sustained and efficient release over time.

In line with the escalating demand for natural and eco-friendly alternatives, pullulan emerges as a sustainable choice for dental product manufacturers. Its biodegradable properties mitigate environmental impact, contrasting favorably with certain synthetic alternatives. Thus, pullulan presents a versatile and eco-conscious solution for enhancing various aspects of dental care formulations.

Pullulan Used in Oral Care

Our pullulan is a white, odorless powder that is highly soluble in water and almost insoluble in ethanol and other organic solvents. A 10% aqueous solution has a pH of 5.0–7.0. Pullulan film is thin, transparent, easily soluble, highly impermeable to oxygen, fat-resistant, odorless, colorless and biodegradable.

Storage typeKeep sealed and store in a dry and cool place
Shelf life24 months
ManufacturerShandong Mimei Biological Co., Ltd.
Raw materialNot applicable
Instructions for useFood additives
Product namePullulan
AppearanceWhite powder
GradeFood Grade Pullulan
>pH value5.0~8.0
SampleFree of charge
Shelf life2 years

Applications in Oral Care

Dental Films and Coatings: Pullulan's film-forming properties make it an ideal ingredient for dental films and coatings. These thin films can be applied to the surface of teeth to provide a protective barrier against plaque formation, bacterial adhesion, and acid erosion. Furthermore, pullulan films can contain active ingredients such as antimicrobials or remineralizing agents, enhancing their therapeutic efficacy.

Oral Care Products: Pullulan is increasingly incorporated into various oral care products such as toothpaste, mouthwash, and chewing gum. In toothpaste formulations, pullulan acts as a binder and thickening agent, improving the texture and stability of the product. Its adhesive properties help to ensure prolonged contact of active ingredients with the tooth surface, enhancing their effectiveness in combating dental plaque and gingival inflammation.

Controlled Release Systems: Pullulan-based delivery systems offer a promising approach for the controlled release of active ingredients in oral care formulations. By encapsulating bioactive compounds within pullulan matrices, sustained release profiles can be achieved, prolonging their therapeutic effects and improving patient compliance. This technology holds potential for targeted delivery of antimicrobial agents, fluoride, or desensitizing agents to specific oral sites, thereby maximizing efficacy while minimizing adverse effects.

Benefits of Pullulan in Oral Care

Plaque Inhibition: Pullulan's film-forming properties inhibit bacterial adhesion to tooth surfaces, reducing plaque formation and the risk of dental caries.

Enhanced Remineralization: Pullulan-based formulations can facilitate the remineralization of enamel by promoting the uptake of essential minerals such as calcium and phosphate.

Improved Sensory Experience: Pullulan contributes to the smooth texture and pleasant mouthfeel of oral care products, enhancing user experience and compliance with oral hygiene regimens.

Biocompatibility and Safety: Pullulan is derived from natural sources and is well-tolerated by oral tissues, making it suitable for individuals with sensitive gums or allergies to synthetic ingredients.

Future Directions

As research into pullulan's applications in oral care continues to expand, future developments may focus on optimizing formulations for specific dental indications, exploring synergistic effects with other active ingredients, and evaluating long-term clinical outcomes. Furthermore, advancements in nanotechnology and biomaterial engineering hold promise for the development of innovative pullulan-based delivery systems with enhanced therapeutic efficacy and targeted action.


Pullulan represents a versatile and promising ingredient in oral care formulations, offering multiple benefits including plaque inhibition, remineralization, and enhanced product stability. With its biocompatibility, safety profile, and multifunctional properties, pullulan is poised to play a significant role in the future of dental health, contributing to improved oral hygiene and overall well-being.

Pullulan for Oral Care Manufacturer

Shandong Mimei Biotechnology Co., Ltd. is a well-known leader in the manufacturing and supply of pullulan and related biological polysaccharide products. Leveraging our expertise and state-of-the-art facilities, we are committed to providing premium quality Pullulan solutions to oral care manufacturers across the globe.

The company has advanced production facilities with an annual output of 3,000 tons of pullulan. We are committed to excellence and have ISO22000, ISO14001 and ISO45001 quality system certifications, in addition to our organic, kosher and halal certifications, ensuring compliance with the most stringent industry standards.

Partner with us to provide superior pullulan solutions to meet the diverse needs of oral care manufacturers. Enhance your formulas with our premium pullulan, known for its superior performance, purity and safety. Experience the difference with Shandong Mimei Biotechnology Co., Ltd., your trusted partner for premium pullulan solutions in oral care manufacturing.

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